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BRCA promoter methylation in sporadic versus BRCA germline mutation-related breast cancers

BACKGROUND: In breast cancer, BRCA promoter hypermethylation and BRCA germline mutations are said to occur together rarely, but this property has not yet been translated into a clinical test. Our aim in this study was to investigate the diagnostic value of BRCA1/2 methylation in distinguishing breas...

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Dettagli Bibliografici
Pubblicato in:Breast Cancer Res
Autori principali: Vos, Shoko, Moelans, Cathy Beatrice, van Diest, Paul Joannes
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5452400/
https://ncbi.nlm.nih.gov/pubmed/28569220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-017-0856-z
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