Contribution of BRCA1 germline mutation in patients with sporadic breast cancer

Hereditary artifacts in BRCA1 gene have a significant contributory role in familial cases of breast cancer. However, its germline mutational penetrance in sporadic breast cancer cases with respect to Pakistani population has not yet been very well defined. This study was designed to assess the contr...

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Bibliografiske detaljer
Main Authors: Malik, Fraz A, Ashraf, Saima, Kayani, Mahmood A, Jiang, Wen G, Mir, A, Ansar, M, Baloch, Ishraat A, Sadiq, Rafshan
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2008
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2538523/
https://ncbi.nlm.nih.gov/pubmed/18759965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-7800-5-21
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