Activity Clamp Provides Insights into Paradoxical Effects of the Anti-Seizure Drug Carbamazepine

A major challenge in experimental epilepsy research is to reconcile the effects of anti-epileptic drugs (AEDs) on individual neurons with their network-level actions. Highlighting this difficulty, it is unclear why carbamazepine (CBZ), a frontline AED with a known molecular mechanism, has been repor...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Morris, Gareth, Leite, Marco, Kullmann, Dimitri M., Pavlov, Ivan, Schorge, Stephanie, Lignani, Gabriele
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2017
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5452340/
https://ncbi.nlm.nih.gov/pubmed/28473648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3697-16.2017
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