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Are Anticapsular Antibodies the Primary Mechanism of Protection against Invasive Pneumococcal Disease?

BACKGROUND: Antibody to capsular polysaccharide has been the basis of several vaccines that offer protection against invasive disease from Streptococcus pneumoniae. The success of such vaccines has led to the inference that natural protection against invasive pneumococcal disease is largely conferre...

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Bibliographic Details
Main Authors: Lipsitch, Marc, Whitney, Cynthia G, Zell, Elizabeth, Kaijalainen, Tarja, Dagan, Ron, Malley, Richard
Format: Artigo
Language:Inglês
Published: Public Library of Science 2005
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC545206/
https://ncbi.nlm.nih.gov/pubmed/15696204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0020015
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