Structural basis for ligand capture and release by the endocytic receptor ApoER2

Apolipoprotein E receptor 2 (ApoER2) is a close homologue of low‐density lipoprotein receptor (LDLR) that mediates the endocytosis of ligands, including LDL particles. LDLR family members have been presumed to explore a large conformational space to capture ligands in the extended conformation at th...

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Vydáno v:EMBO Rep
Hlavní autoři: Hirai, Hidenori, Yasui, Norihisa, Yamashita, Keitaro, Tabata, Sanae, Yamamoto, Masaki, Takagi, Junichi, Nogi, Terukazu
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2017
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Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5452030/
https://ncbi.nlm.nih.gov/pubmed/28446613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201643521
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