Independent effects of ADH1B and ALDH2 common dysfunctional variants on gout risk

Gout is caused by hyperuricemia, with alcohol consumption being an established risk factor. Alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) are crucial enzymes for alcohol metabolism. We recently performed a genome-wide association study of gout and a subsequent fine-mapping study whic...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Sakiyama, Masayuki, Matsuo, Hirotaka, Akashi, Airi, Shimizu, Seiko, Higashino, Toshihide, Kawaguchi, Makoto, Nakayama, Akiyoshi, Naito, Mariko, Kawai, Sayo, Nakashima, Hiroshi, Sakurai, Yutaka, Ichida, Kimiyoshi, Shimizu, Toru, Ooyama, Hiroshi, Shinomiya, Nariyoshi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5451470/
https://ncbi.nlm.nih.gov/pubmed/28566767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02528-z
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