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FastGT: an alignment-free method for calling common SNVs directly from raw sequencing reads
We have developed a computational method that counts the frequencies of unique k-mers in FASTQ-formatted genome data and uses this information to infer the genotypes of known variants. FastGT can detect the variants in a 30x genome in less than 1 hour using ordinary low-cost server hardware. The ove...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5451431/ https://ncbi.nlm.nih.gov/pubmed/28566690 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02487-5 |
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