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Targeted radionuclide therapy with astatine-211: Oxidative dehalogenation of astatobenzoate conjugates

(211)At is a most promising radionuclide for targeted alpha therapy. However, its limited availability and poorly known basic chemistry hamper its use. Based on the analogy with iodine, labelling is performed via astatobenzoate conjugates, but in vivo deastatination occurs, particularly when the con...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Sci Rep
Κύριοι συγγραφείς: Teze, David, Sergentu, Dumitru-Claudiu, Kalichuk, Valentina, Barbet, Jacques, Deniaud, David, Galland, Nicolas, Maurice, Rémi, Montavon, Gilles
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Nature Publishing Group UK 2017
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5451414/
https://ncbi.nlm.nih.gov/pubmed/28566709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02614-2
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