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A PPARγ-dependent miR-424/503-CD40 axis regulates inflammation mediated angiogenesis

Activation of the endothelium by pro-inflammatory stimuli plays a key role in the pathogenesis of a multitude of vascular diseases. Angiogenesis is a crucial component of the vascular response associated with inflammatory signaling. The CD40/CD40 ligand dyad in endothelial cells (EC) has a central r...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Lee, Aram, Papangeli, Irinna, Park, Youngsook, Jeong, Ha-neul, Choi, Jihea, Kang, Hyesoo, Jo, Ha-neul, Kim, Jongmin, Chun, Hyung J.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5451412/
https://ncbi.nlm.nih.gov/pubmed/28566713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02852-4
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