Loss of PPARγ in endothelial cells leads to impaired angiogenesis

Tie2-promoter-mediated loss of peroxisome proliferator-activated receptor gamma (PPARγ, also known as PPARG) in mice leads to osteopetrosis and pulmonary arterial hypertension. Vascular disease is associated with loss of PPARγ in pulmonary microvascular endothelial cells (PMVEC); we evaluated the ro...

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Udgivet i:J Cell Sci
Main Authors: Vattulainen-Collanus, Sanna, Akinrinade, Oyediran, Li, Molong, Koskenvuo, Minna, Li, Caiyun Grace, Rao, Shailaja P., de Jesus Perez, Vinicio, Yuan, Ke, Sawada, Hirofumi, Koskenvuo, Juha W., Alvira, Cristina, Rabinovitch, Marlene, Alastalo, Tero-Pekka
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Ltd 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5108588/
https://ncbi.nlm.nih.gov/pubmed/26743080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.169011
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