Molecular isoforms of high-mobility group box 1 are mechanistic biomarkers for epilepsy

Approximately 30% of epilepsy patients do not respond to antiepileptic drugs, representing an unmet medical need. There is evidence that neuroinflammation plays a pathogenic role in drug-resistant epilepsy. The high-mobility group box 1 (HMGB1)/TLR4 axis is a key initiator of neuroinflammation follo...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:J Clin Invest
Asıl Yazarlar: Walker, Lauren Elizabeth, Frigerio, Federica, Ravizza, Teresa, Ricci, Emanuele, Tse, Karen, Jenkins, Rosalind E., Sills, Graeme John, Jorgensen, Andrea, Porcu, Luca, Thippeswamy, Thimmasettappa, Alapirtti, Tiina, Peltola, Jukka, Brodie, Martin J., Park, Brian Kevin, Marson, Anthony Guy, Antoine, Daniel James, Vezzani, Annamaria, Pirmohamed, Munir
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2017
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5451237/
https://ncbi.nlm.nih.gov/pubmed/28504645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI92001
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller