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Evaluation of the effect of recombinant thrombomodulin on a lipopolysaccharide-induced murine sepsis model

To evaluate the effect of recombinant human thrombomodulin (rTM) on sepsis, the levels of nucleosome as well as high-mobility group box 1 (HMGB1) and cytokines in sera and peritoneal fluids were measured in a mouse model of lipopolysaccharide (LPS)-induced sepsis after administration of rTM. C57BL/6...

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Bibliografski detalji
Izdano u:Exp Ther Med
Glavni autori: Takehara, Kazuhiro, Murakami, Taisuke, Kuwahara-Arai, Kyoko, Iba, Toshiaki, Nagaoka, Isao, Sakamoto, Kazuhiro
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5450552/
https://ncbi.nlm.nih.gov/pubmed/28587368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2017.4308
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