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Combination effect of antithrombin and recombinant human soluble thrombomodulin in a lipopolysaccharide induced rat sepsis model

INTRODUCTION: Recombinant human soluble thrombomodulin (rhsTM) is newly developed for the treatment of DIC. The purpose of this study was to evaluate the efficacy of the concomitant administration of rhsTM and antithrombin (AT). METHODS: In the first series, rats were treated with either 62.5, 125,...

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Detalhes bibliográficos
Main Authors: Iba, Toshiaki, Nakarai, Etsuro, Takayama, Toshio, Nakajima, Kenji, Sasaoka, Tetsumasa, Ohno, Yoichi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2811901/
https://ncbi.nlm.nih.gov/pubmed/20003418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc8210
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