Combination effect of antithrombin and recombinant human soluble thrombomodulin in a lipopolysaccharide induced rat sepsis model

INTRODUCTION: Recombinant human soluble thrombomodulin (rhsTM) is newly developed for the treatment of DIC. The purpose of this study was to evaluate the efficacy of the concomitant administration of rhsTM and antithrombin (AT). METHODS: In the first series, rats were treated with either 62.5, 125,...

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Bibliografski detalji
Glavni autori: Iba, Toshiaki, Nakarai, Etsuro, Takayama, Toshio, Nakajima, Kenji, Sasaoka, Tetsumasa, Ohno, Yoichi
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2009
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2811901/
https://ncbi.nlm.nih.gov/pubmed/20003418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc8210
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