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Combination effect of antithrombin and recombinant human soluble thrombomodulin in a lipopolysaccharide induced rat sepsis model

INTRODUCTION: Recombinant human soluble thrombomodulin (rhsTM) is newly developed for the treatment of DIC. The purpose of this study was to evaluate the efficacy of the concomitant administration of rhsTM and antithrombin (AT). METHODS: In the first series, rats were treated with either 62.5, 125,...

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Bibliographische Detailangaben
Hauptverfasser: Iba, Toshiaki, Nakarai, Etsuro, Takayama, Toshio, Nakajima, Kenji, Sasaoka, Tetsumasa, Ohno, Yoichi
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2811901/
https://ncbi.nlm.nih.gov/pubmed/20003418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc8210
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