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Solvation and surface effects on polymorph stabilities at the nanoscale

We explore the effects of particle size and solvent environment on the thermodynamic stability of two pairs of polymorphs subjected to ball-mill neat grinding (NG) and liquid assisted grinding (LAG). Two systems were studied: (i) forms I and II of a 1 : 1 theophylline : benzamide cocrystal and (ii)...

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Bibliografske podrobnosti
izdano v:Chem Sci
Main Authors: Belenguer, A. M., Lampronti, G. I., Cruz-Cabeza, A. J., Hunter, C. A., Sanders, J. K. M.
Format: Artigo
Jezik:Inglês
Izdano: Royal Society of Chemistry 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5450528/
https://ncbi.nlm.nih.gov/pubmed/28567252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc03457h
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