Modelling pulmonary microthrombosis coupled to metastasis: distinct effects of thrombogenesis on tumorigenesis

Thrombosis can cause localized ischemia and tissue hypoxia, and both of these are linked to cancer metastasis. Vascular micro-occlusion can occur as a result of arrest of circulating tumour cells in small capillaries, giving rise to microthrombotic events that affect flow, creating localized hypoxic...

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Detalhes bibliográficos
Publicado no:Biol Open
Main Authors: Evans, Colin E., Palazon, Asis, Sim, Jingwei, Tyrakis, Petros A., Prodger, Alice, Lu, Xiao, Chan, Saria, Bendahl, Pär-Ola, Belting, Mattias, Von Euler, Love, Rundqvist, Helene, Johnson, Randall S., Branco, Cristina
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2017
Assuntos:
Methods & Techniques
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5450329/
https://ncbi.nlm.nih.gov/pubmed/28302670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.024653
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