Evaluating the accuracy of amplicon-based microbiome computational pipelines on simulated human gut microbial communities

BACKGROUND: Microbiome studies commonly use 16S rRNA gene amplicon sequencing to characterize microbial communities. Errors introduced at multiple steps in this process can affect the interpretation of the data. Here we evaluate the accuracy of operational taxonomic unit (OTU) generation, taxonomic...

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Detaylı Bibliyografya
Yayımlandı:BMC Bioinformatics
Asıl Yazarlar: Golob, Jonathan L., Margolis, Elisa, Hoffman, Noah G., Fredricks, David N.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2017
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5450146/
https://ncbi.nlm.nih.gov/pubmed/28558684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-017-1690-0
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