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Evaluating the accuracy of amplicon-based microbiome computational pipelines on simulated human gut microbial communities
BACKGROUND: Microbiome studies commonly use 16S rRNA gene amplicon sequencing to characterize microbial communities. Errors introduced at multiple steps in this process can affect the interpretation of the data. Here we evaluate the accuracy of operational taxonomic unit (OTU) generation, taxonomic...
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| Publicado no: | BMC Bioinformatics |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5450146/ https://ncbi.nlm.nih.gov/pubmed/28558684 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-017-1690-0 |
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