Long-term leukocyte reconstitution in NSG mice transplanted with human cord blood hematopoietic stem and progenitor cells

BACKGROUND: Humanized mice (hu mice) are based on the transplantation of hematopoietic stem and progenitor cells into immunodeficient mice and have become important pre-clinical models for biomedical research. However, data about their hematopoiesis over time are scarce. We therefore characterized l...

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Publicado en:BMC Immunol
Autores principales: Audigé, Annette, Rochat, Mary-Aude, Li, Duo, Ivic, Sandra, Fahrny, Audrey, Muller, Christina K. S., Gers-Huber, Gustavo, Myburgh, Renier, Bredl, Simon, Schlaepfer, Erika, Scherrer, Alexandra U., Kuster, Stefan P., Speck, Roberto F.
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5450051/
https://ncbi.nlm.nih.gov/pubmed/28558649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12865-017-0209-9
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