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A branch-migration based fluorescent probe for straightforward, sensitive and specific discrimination of DNA mutations

Genetic mutations are important biomarkers for cancer diagnostics and surveillance. Preferably, the methods for mutation detection should be straightforward, highly specific and sensitive to low-level mutations within various sequence contexts, fast and applicable at room-temperature. Though some of...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Xiao, Xianjin, Wu, Tongbo, Xu, Lei, Chen, Wei, Zhao, Meiping
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5449635/
https://ncbi.nlm.nih.gov/pubmed/28201758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx117
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