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Conformation-sensitive nucleoside analogues as topology-specific fluorescence turn-on probes for DNA and RNA G-quadruplexes

Development of probes that can discriminate G-quadruplex (GQ) structures and indentify efficient GQ binders on the basis of topology and nucleic acid type is highly desired to advance GQ-directed therapeutic strategies. In this context, we describe the development of minimally perturbing and environ...

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發表在:Nucleic Acids Res
Main Authors: Tanpure, Arun A., Srivatsan, Seergazhi G.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4678839/
https://ncbi.nlm.nih.gov/pubmed/26202965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv743
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