A sensitivity analysis of RNA folding nearest neighbor parameters identifies a subset of free energy parameters with the greatest impact on RNA secondary structure prediction

Nearest neighbor parameters for estimating the folding energy changes of RNA secondary structures are used in structure prediction and analysis. Despite their widespread application, a comprehensive analysis of the impact of each parameter on the precision of calculations had not been conducted. To...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Zuber, Jeffrey, Sun, Hongying, Zhang, Xiaoju, McFadyen, Iain, Mathews, David H.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5449625/
https://ncbi.nlm.nih.gov/pubmed/28334976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx170
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