Impaired Relaxation of Airway Smooth Muscle in Mice Lacking the Actin-Binding Protein Gelsolin

Diverse classes of ligands have recently been discovered that relax airway smooth muscle (ASM) despite a transient increase in intracellular calcium concentrations ([Ca(2+)](i)). However, the cellular mechanisms are not well understood. Gelsolin is a calcium-activated actin-severing and -capping pro...

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Enregistré dans:
Détails bibliographiques
Publié dans:Am J Respir Cell Mol Biol
Auteurs principaux: Mikami, Maya, Zhang, Yi, Danielsson, Jennifer, Joell, Tiarra, Yong, Hwan Mee, Townsend, Elizabeth, Khurana, Seema, An, Steven S., Emala, Charles W.
Format: Artigo
Langue:Inglês
Publié: American Thoracic Society 2017
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5449493/
https://ncbi.nlm.nih.gov/pubmed/28118027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2016-0292OC
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