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Insulin expressing hepatocytes not destroyed in transgenic NOD mice

BACKGROUND: The liver has been suggested as a suitable target organ for gene therapy of Type 1 diabetes. However, the fundamental issue whether insulin-secreting hepatocytes in vivo will be destroyed by the autoimmune processes that kill pancreatic β cells has not been fully addressed. It is possibl...

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Détails bibliographiques
Publié dans:J Autoimmune Dis
Auteurs principaux: Tabiin, Muhammad T, White, Christopher P, Morahan, Grant, Tuch, Bernard E
Format: Artigo
Langue:Inglês
Publié: BMC 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC544947/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15679918/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1740-2557-1-3
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