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Insulin expressing hepatocytes not destroyed in transgenic NOD mice
BACKGROUND: The liver has been suggested as a suitable target organ for gene therapy of Type 1 diabetes. However, the fundamental issue whether insulin-secreting hepatocytes in vivo will be destroyed by the autoimmune processes that kill pancreatic β cells has not been fully addressed. It is possibl...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC544947/ https://ncbi.nlm.nih.gov/pubmed/15679918 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1740-2557-1-3 |
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