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Regulation of human insulin gene expression in transgenic mice

Insulin is a polypeptide hormone of major physiological importance in the regulation of fuel homeostasis in animals (reviewed in refs 1, 2). It is synthesized by the (β)-cells of pancreatic islets, and circulating insulin levels are regulated by several small molecules, notably glucose, amino acids,...

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Pubblicato in:Nature
Autori principali: Selden, Richard F, Skośkiewicz, Marek J., Howie, Kathleen Burke, Russell, Paul S., Goodman, Howard M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 1986
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7095452/
https://ncbi.nlm.nih.gov/pubmed/3520336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/321525a0
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