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Susceptibility to liver fibrosis in mice expressing a connective tissue growth factor transgene in hepatocytes
Connective tissue growth factor (CCN2) is a matricellular protein that is up-regulated in many fibrotic disorders and co-expressed with transforming growth factor beta. CCN2 promotes fibrogenesis and survival in activated hepatic stellate cells, and injured or fibrotic liver contains up-regulated le...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2737071/ https://ncbi.nlm.nih.gov/pubmed/19670427 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.23102 |
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