The force-sensing peptide VemP employs extreme compaction and secondary structure formation to induce ribosomal stalling

Interaction between the nascent polypeptide chain and the ribosomal exit tunnel can modulate the rate of translation and induce translational arrest to regulate expression of downstream genes. The ribosomal tunnel also provides a protected environment for initial protein folding events. Here, we pre...

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Bibliografske podrobnosti
izdano v:eLife
Main Authors: Su, Ting, Cheng, Jingdong, Sohmen, Daniel, Hedman, Rickard, Berninghausen, Otto, von Heijne, Gunnar, Wilson, Daniel N, Beckmann, Roland
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2017
Teme:
Biochemistry
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5449182/
https://ncbi.nlm.nih.gov/pubmed/28556777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.25642
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