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Dietary constituent, decanoic acid suppresses the excitability of nociceptive trigeminal neuronal activity associated with hypoalgesia via muscarinic M(2) receptor signaling

BACKGROUND: Although decanoic acid (DA) is thought to act as a muscarinic cholinergic agonist, effect of DA on nociceptive behavioral responses and the excitability of nociceptive neuronal activity under in vivo conditions remain to be determined. The aim of the present study, therefore, was to inve...

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Pubblicato in:Mol Pain
Autori principali: Noguchi, Yuna, Matsuzawa, Nichiwa, Akama, Youichi, Sekiguchi, Kenta, Takehana, Shiori, Shimazu, Yoshihito, Takeda, Mamoru
Natura: Artigo
Lingua:Inglês
Pubblicazione: SAGE Publications 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5448867/
https://ncbi.nlm.nih.gov/pubmed/28474958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1744806917710779
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