Novel small molecule inhibiting CDCP1‐PKCδ pathway reduces tumor metastasis and proliferation

CUB domain‐containing protein‐1 (CDCP1) is a trans‐membrane protein predominantly expressed in various cancer cells and involved in tumor progression. CDCP1 is phosphorylated at tyrosine residues in the intracellular domain by Src family kinases and recruits PKCδ to the plasma membrane through tyros...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cancer Sci
Egile Nagusiak: Nakashima, Katsuhiko, Uekita, Takamasa, Yano, Shigenobu, Kikuchi, Jun‐ichi, Nakanishi, Ruri, Sakamoto, Nozomi, Fukumoto, Keisuke, Nomoto, Akihiro, Kawamoto, Keisuke, Shibahara, Takashi, Yamaguchi, Hideki, Sakai, Ryuichi
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2017
Gaiak:
Original Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5448658/
https://ncbi.nlm.nih.gov/pubmed/28256037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13218
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