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Novel small molecule inhibiting CDCP1‐PKCδ pathway reduces tumor metastasis and proliferation
CUB domain‐containing protein‐1 (CDCP1) is a trans‐membrane protein predominantly expressed in various cancer cells and involved in tumor progression. CDCP1 is phosphorylated at tyrosine residues in the intracellular domain by Src family kinases and recruits PKCδ to the plasma membrane through tyros...
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| Publié dans: | Cancer Sci |
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| Auteurs principaux: | , , , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
John Wiley and Sons Inc.
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5448658/ https://ncbi.nlm.nih.gov/pubmed/28256037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13218 |
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