Novel small molecule inhibiting CDCP1‐PKCδ pathway reduces tumor metastasis and proliferation

CUB domain‐containing protein‐1 (CDCP1) is a trans‐membrane protein predominantly expressed in various cancer cells and involved in tumor progression. CDCP1 is phosphorylated at tyrosine residues in the intracellular domain by Src family kinases and recruits PKCδ to the plasma membrane through tyros...

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Bibliografiske detaljer
Udgivet i:Cancer Sci
Main Authors: Nakashima, Katsuhiko, Uekita, Takamasa, Yano, Shigenobu, Kikuchi, Jun‐ichi, Nakanishi, Ruri, Sakamoto, Nozomi, Fukumoto, Keisuke, Nomoto, Akihiro, Kawamoto, Keisuke, Shibahara, Takashi, Yamaguchi, Hideki, Sakai, Ryuichi
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5448658/
https://ncbi.nlm.nih.gov/pubmed/28256037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13218
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