Coexistence of KRAS and BRAF Mutations in Colorectal Cancer: A Case Report Supporting The Concept of Tumoral Heterogeneity

The detection of KRAS and BRAF mutations is a crucial step for the correct therapeutic approach and predicting the epidermal growth factor receptor (EGFR)-targeted therapy resistance of colorectal carcinomas. The concomitant KRAS and BRAF mutations occur rarely in the colorectal cancers (CRCs) with...

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Detalhes bibliográficos
Publicado no:Cell J
Main Authors: Larki, Pegah, Gharib, Ehsan, Yaghoob Taleghani, Mohammad, Khorshidi, Fatemeh, Nazemalhosseini-Mojarad, Ehsan, Asadzadeh Aghdaei, Hamid
Formato: Artigo
Idioma:Inglês
Publicado em: Royan Institute 2017
Assuntos:
Case Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5448326/
https://ncbi.nlm.nih.gov/pubmed/28580315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22074/cellj.2017.5123
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