Coexistence of KRAS and BRAF Mutations in Colorectal Cancer: A Case Report Supporting The Concept of Tumoral Heterogeneity

The detection of KRAS and BRAF mutations is a crucial step for the correct therapeutic approach and predicting the epidermal growth factor receptor (EGFR)-targeted therapy resistance of colorectal carcinomas. The concomitant KRAS and BRAF mutations occur rarely in the colorectal cancers (CRCs) with...

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Publicado en:Cell J
Autores principales: Larki, Pegah, Gharib, Ehsan, Yaghoob Taleghani, Mohammad, Khorshidi, Fatemeh, Nazemalhosseini-Mojarad, Ehsan, Asadzadeh Aghdaei, Hamid
Formato: Artigo
Lenguaje:Inglês
Publicado: Royan Institute 2017
Materias:
Case Report
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5448326/
https://ncbi.nlm.nih.gov/pubmed/28580315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22074/cellj.2017.5123
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