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Atypical interactions of integrin α(V)β(8) with pro-TGF-β1
Integrins α(V)β(6) and α(V)β(8) are specialized for recognizing pro-TGF-β and activating its growth factor by releasing it from the latency imposed by its surrounding prodomain. The integrin α(V)β(8) is atypical among integrins in lacking sites in its cytoplasmic domain for binding to actin cytoskel...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5448207/ https://ncbi.nlm.nih.gov/pubmed/28484027 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1705129114 |
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