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Targeting Hypoxia Inducible Factors-1α As a Novel Therapy in Fibrosis
Fibrosis, characterized by increased extracellular matrix (ECM) deposition, and widespread vasculopathy, has the prominent trait of chronic hypoxia. Hypoxia inducible factors-1α (HIF-1α), a key transcriptional factor in response to this chronic hypoxia, is involved in fibrotic disease, such as Syste...
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| Publicado no: | Front Pharmacol |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5447768/ https://ncbi.nlm.nih.gov/pubmed/28611671 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00326 |
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