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Designer protein disaggregases to counter neurodegenerative disease

Protein misfolding and aggregation unify several devastating neurodegenerative disorders, including Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis. There are no effective therapeutics for these disorders and none that target the reversal of the aberrant protein misfoldin...

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Podrobná bibliografie
Vydáno v:Curr Opin Genet Dev
Hlavní autor: Shorter, James
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5447488/
https://ncbi.nlm.nih.gov/pubmed/28208059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2017.01.008
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