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Designer protein disaggregases to counter neurodegenerative disease

Protein misfolding and aggregation unify several devastating neurodegenerative disorders, including Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis. There are no effective therapeutics for these disorders and none that target the reversal of the aberrant protein misfoldin...

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Bibliographic Details
Published in:Curr Opin Genet Dev
Main Author: Shorter, James
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5447488/
https://ncbi.nlm.nih.gov/pubmed/28208059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2017.01.008
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