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Metabolic Labeling and Recovery of Nascent RNA to Accurately Quantify mRNA Stability

Changes in the rate of mRNA decay are closely coordinated with transcriptional changes and together these events have profound effects on gene expression during development and disease. Traditional approaches to assess mRNA decay have relied on inhibition of transcription, which can alter mRNA decay...

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Detaylı Bibliyografya
Yayımlandı:Methods
Asıl Yazarlar: Russo, Joseph, Heck, Adam M., Wilusz, Jeffrey, Wilusz, Carol J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5447484/
https://ncbi.nlm.nih.gov/pubmed/28219744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2017.02.003
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