Coenzyme A thioester formation of 11- and 15-oxo-eicosatetraenoic acid

Release of arachidonic acid (AA) by cytoplasmic phospholipase A2 (cPLA2), followed by metabolism through cyclooxygenase-2 (COX-2) and 15-hydroxyprostaglandin dehydrogenase (15-PGDH), results in the formation of the eicosanoids 11-oxo- and 15-oxo-eicosatetraenoic acid (oxo-ETE). Both 11-oxo- and 15-o...

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Udgivet i:Prostaglandins Other Lipid Mediat
Main Authors: Mesaros, Clementina, Arroyo, Alejandro D., Blair, Ian A., Snyder, Nathaniel W.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5446925/
https://ncbi.nlm.nih.gov/pubmed/28238887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.prostaglandins.2017.02.004
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