Dendritic cells combined with tumor cells and α-galactosylceramide induce a potent, therapeutic and NK-cell dependent antitumor immunity in B cell lymphoma

BACKGROUND: Invariant natural killer T (iNKT) cells are a small population of lymphocytes with unique specificity for glycolipid antigens presented by non-polymorphic CD1d receptor on dendritic cells (DCs). iNKT cells play a central role in tumor immunology since they are implicated in the coordinat...

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Publicat a:J Transl Med
Autors principals: Escribà-Garcia, Laura, Alvarez-Fernández, Carmen, Tellez-Gabriel, Marta, Sierra, Jorge, Briones, Javier
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5446707/
https://ncbi.nlm.nih.gov/pubmed/28549432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-017-1219-3
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