Memory stem T cells modified with a redesigned CD30‐chimeric antigen receptor show an enhanced antitumor effect in Hodgkin lymphoma

OBJECTIVES: Adoptive cell therapy (ACT) with mature T cells modified with a chimeric antigen receptor has demonstrated improved outcome for B‐cell malignancies. However, its application for others such as Hodgkin lymphoma remains a clinical challenge. CD30 antigen, expressed in Hodgkin lymphoma cell...

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Publicat a:Clin Transl Immunology
Autors principals: Alvarez‐Fernández, Carmen, Escribà‐Garcia, Laura, Caballero, AC, Escudero‐López, Eva, Ujaldón‐Miró, Cristina, Montserrat‐Torres, Rosanna, Pujol‐Fernández, Paula, Sierra, Jorge, Briones, Javier
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2021
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8082716/
https://ncbi.nlm.nih.gov/pubmed/33968404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cti2.1268
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