Inhibition of SIRPα in dendritic cells potentiates potent antitumor immunity

Despite their central function in tumor immunity, dendritic cells (DCs) can respond to inhibitory signals and become tolerogenic, curtailing T cell responses in vivo. Here, we provide the evidence for an inhibitory function of signal regulatory protein (SIRP) α in DC survival and activation. In tumo...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Liu, Qiong, Wen, Wen, Tang, Liang, Qin, Chen-Jie, Lin, Yan, Zhang, Hui-Lu, Wu, Han, Ashton, Charles, Wu, Hong-Ping, Ding, Jin, Dong, Wei, Yu, Le-Xing, Yang, Wen, Huang, Dan-Dan, Wu, Meng-Chao, Wang, Hong-Yang, Yan, He-Xin
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5048764/
https://ncbi.nlm.nih.gov/pubmed/27757296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1183850
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