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Pharmacological modulators of autophagy activate a parallel noncanonical pathway driving unconventional LC3 lipidation
The modulation of canonical macroautophagy/autophagy for therapeutic benefit is an emerging strategy of medical and pharmaceutical interest. Many drugs act to inhibit autophagic flux by targeting lysosome function, while others were developed to activate the pathway. Here, we report the surprising f...
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| Pubblicato in: | Autophagy |
|---|---|
| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Taylor & Francis
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5446083/ https://ncbi.nlm.nih.gov/pubmed/28296541 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2017.1287653 |
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