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Identification of a nucleotide exchange-promoting activity for p21ras.

The biological activity of proteins encoded by the ras family of oncogenes is dependent on whether they are bound to GTP or GDP: the type of nucleotide bound is dependent on the rate of GTP hydrolysis (promoted by the GTPase-activating protein, GAP) and the rate of nucleotide exchange with cytosolic...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Downward, J, Riehl, R, Wu, L, Weinberg, R A
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1990
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54457/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2116014/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.15.5998
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