Comparison of Sirtuin 3 Levels in ALS and Huntington’s Disease—Differential Effects in Human Tissue Samples vs. Transgenic Mouse Models

Neurodegenerative diseases are characterized by distinct patterns of neuronal loss. In amyotrophic lateral sclerosis (ALS) upper and lower motoneurons degenerate whereas in Huntington’s disease (HD) medium spiny neurons in the striatum are preferentially affected. Despite these differences the patho...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Buck, Eva, Bayer, Hanna, Lindenberg, Katrin S., Hanselmann, Johannes, Pasquarelli, Noemi, Ludolph, Albert C., Weydt, Patrick, Witting, Anke
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5445120/
https://ncbi.nlm.nih.gov/pubmed/28603486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00156
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