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Adiponectin attenuates high glucose-induced apoptosis through the AMPK/p38 MAPK signaling pathway in NRK-52E cells

Excessive apoptosis of proximal tubule cell is closely related to the development of diabetes. Recent evidence suggests that adiponectin (ADPN) protects cells from high glucose induced apoptosis. However, the precise mechanisms remain poorly understood. We sought to investigate the role of p38 mitog...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Wang, Yuanyuan, Zhang, Juan, Zhang, Lian, Gao, Ping, Wu, Xiaoyan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5444659/
https://ncbi.nlm.nih.gov/pubmed/28542560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0178215
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