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Biochemical characterization of AP lyase and m(6)A demethylase activities of human AlkB homolog 1 (ALKBH1)

Alkbh1 is one of nine mammalian homologs of Escherichia coli AlkB, a 2-oxoglutarate-dependent dioxygenase that catalyzes direct DNA repair by removing alkyl lesions from DNA. Six distinct enzymatic activities have been reported for Alkbh1, including hydroxylation of variously methylated DNA, mRNA, t...

詳細記述

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書誌詳細
出版年:Biochemistry
主要な著者: Müller, Tina A., Tobar, Michael A., Perian, Madison N., Hausinger, Robert P.
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5444387/
https://ncbi.nlm.nih.gov/pubmed/28290676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b00060
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