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Cryptic Exon Incorporation Occurs in Alzheimer’s Brain lacking TDP-43 Inclusion but Exhibiting Nuclear Clearance of TDP-43
Abnormal accumulation of TDP-43 into cytoplasmic or nuclear inclusions with accompanying nuclear clearance, a common pathology initially identified in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), has also been found in Alzheimer’ disease (AD). TDP-43 serves as a splicing re...
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| 發表在: | Acta Neuropathol |
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| Main Authors: | , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5444385/ https://ncbi.nlm.nih.gov/pubmed/28332094 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-017-1701-2 |
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