Development of a Novel Site-Specific Pegylated Interferon Beta for Antiviral Therapy of Chronic Hepatitis B Virus

Although nucleot(s)ide analogues and pegylated interferon alpha 2a (PEG-IFN-α2a) can suppress hepatitis B virus (HBV) replication, it is difficult to achieve complete HBV elimination from hepatocytes. A novel site-specific pegylated recombinant human IFN-β (TRK-560) was recently developed. In the pr...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Tsuge, Masataka, Uchida, Takuro, Hiraga, Nobuhiko, Kan, Hiromi, Makokha, Grace Naswa, Abe-Chayama, Hiromi, Miki, Daiki, Imamura, Michio, Ochi, Hidenori, Hayes, C. Nelson, Shimozono, Rieko, Iwamura, Tomokatsu, Narumi, Hideki, Suzuki, Tomohiko, Kainoh, Mie, Taniguchi, Tadatsugu, Chayama, Kazuaki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5444133/
https://ncbi.nlm.nih.gov/pubmed/28373196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00183-17
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