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A core extended naphtalene diimide G-quadruplex ligand potently inhibits herpes simplex virus 1 replication
G-quadruplexes (G4s) are nucleic acids secondary structures, epigenetic regulators in cells and viruses. In herpes simplex virus 1 (HSV-1)-infected cells, G4s are massively present during viral replication. We here aimed at investigating the possibility to target the HSV-1 G4s by a core extended nap...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5443766/ https://ncbi.nlm.nih.gov/pubmed/28539620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02667-3 |
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