Mycobacterial Hsp65 antigen upregulates the cellular immune response of healthy individuals compared with tuberculosis patients

Previously we showed that 65-kDa Mycobacterium leprae heat shock protein (Hsp65) is a target for the development of a tuberculosis vaccine. Here we evaluated peripheral blood mononuclear cells (PBMC) from healthy individuals or tuberculosis patients stimulated with two forms of Hsp65 antigen, recomb...

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Detalhes bibliográficos
Publicado no:Hum Vaccin Immunother
Main Authors: Wowk, Pryscilla Fanini, Franco, Luís Henrique, da Fonseca, Denise Morais, Paula, Marina Oliveira, Vianna, Élcio dos Santos Oliveira, Wendling, Ana Paula, Augusto, Valéria Maria, Elói-Santos, Silvana Maria, Teixeira-Carvalho, Andréa, Silva, Flávia Dias Coelho, Vinhas, Solange Alves, Martins-Filho, Olindo Assis, Palaci, Moisés, Silva, Célio Lopes, Bonato, Vânia Luiza Deperon
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5443371/
https://ncbi.nlm.nih.gov/pubmed/28059670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2016.1264547
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