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1,25-(OH)(2)D(3) and its analogue BXL-628 inhibit high glucose-induced activation of RhoA/ROCK pathway in HK-2 cells
It has previously been reported that 1,25-(OH)(2)D(3) inhibits high glucose-induced epithelial-to-mesenchymal transition (EMT) in HK-2 cells. However, the mechanism of this renoprotective action remains unclear. Elocalcitol (BXL-628), a vitamin D analog, has been suggested to be effective on the Rho...
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| Publicado no: | Exp Ther Med |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
D.A. Spandidos
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5443178/ https://ncbi.nlm.nih.gov/pubmed/28565795 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2017.4211 |
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